Monday, August 29, 2005

Pathologist, Biochemist, Activist

Dr. James H McKerrow works to develop innovative treatments for five neglected diseases. Pharmaceutical companies neglect these diseases because they exist outside the target market. These diseases – malaria, schistosomiasis, leishmaniasis – also known as Baghdad Boil – African sleeping sickness, and Chagas’ disease – affect millions and millions of people. Parasites infect the poor. Parasites prosper in poor countries.

Dr. McKerrow obtained funding from a family foundation to purchase innovative machines doing a new style of research testing thousands of options at once. Checking existing drugs (shorter time to market) through the new system quickly resulted in a few promising treatment options.

Without economic inducements, the drug companies are not going to get directly involved. That didn’t stop McKerrow. With new systems of drug manufacturing emerging, Ireland, Puerto Rico, or India have capacity for developing the treatments.

African sleeping sickness and Chagas’ disease both may have new treatments, thanks to Dr. McKerrow. Two out of 5. Good start.

For more, read the NYT article (for $) at http://query.nytimes.com/gst/abstract.html?res=F70E11FA395B0C758EDDAE0894DD404482&incamp=archive:search. This article posted on July 26, 2005.

Please share with us your stories of people using their time, talents, and resources toward the common good.

Dr. McKerrow used his talent, found a reasonable and specific action to take, and worked past the existing barriers to develop treatments that can change millions of lives. We honor Dr. McKerrow as a MAD Maven.

Tuesday, February 08, 2005

Welcome

Thanks for joining us here at MAD Mavens. We look forward to many great conversations about how to make a difference.

We would love to know what you are interested in reading about.
Our webmag covers:
Making a Difference in Action (MADness in Action)--stories about how people go about making a difference.
Technical Opportunities--brief examinations into tactics and stratgies that can be useful in financial planning and specifically charitable planning. Watch for the Darwin Award and Homer's Doh! stories on what to avoid.
High Impact Giving--stories about making a better more impactful optimized difference. Basically, what makes a cause tip and how to tip it.
Family Wealth--stories about multigenerational planning as well as tips for creating family connections and sharing values.
First Half--stories about options unique to people in the first half of life raning from kids making a difference to social venture investing and socially responsible investing.
Second Half--stories about the second half of life and how to make it your best half, financial independence (commonly called retirement), and legacy making.
Coach Corner--Reflections and insights from a life coaching.
Reporting from the Future--Using innovative prediction techniques, we forcast what the table of contents might look like at a specified future date.
Reviews
Monthly Workout--Exercise your brain.